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This article was co-written by Mark Ziats, MD, PhD. Dr. Ziats is an internist, researcher and entrepreneur in biotechnology. He received his PhD in Genetics from the University of Cambridge in 2014 and completed his MD shortly thereafter, at Baylor College of Medicine in 2015.
There are 13 references cited in this article that you can view at the bottom of the page.
This article has been viewed 3,828 times.
Glutamine is an amino acid involved in the production of protein, which is essential for muscle health, endurance and the body’s ability to recover. Although glutamine is produced by the body and also obtained through dietary sources, when the body is under stress, certain cells such as those of the immune system require higher levels of glutamine to function properly. function properly. [1 ] X Research Source Newshpme P. Why is L-glutamine metabpism important to cells of the immune system in health, postinjury, surgery or infection? J Nutr. 2001 Sep;131(9 Suppl):2515S-22S; discussion 2523S-4S.
Steps
Understanding glutamine
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Learn about glutamine yourself. Glutamine is an amino acid produced by the body. Amino acids are the basic building blocks of proteins, playing an important role in the growth and functioning of cells. [2] X Trusted Source Mayo Clinic Go to Source Specifically, glutamine helps remove waste products called ammonia from the body, and also supports the immune system and digestion.
- Glutamine is stored in the muscles and lungs. [3] X Research Sources
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Find natural sources of glutamine. Normally, most of the necessary glutamine is produced by the body and received through the daily diet. However, when the body is under stress, it cannot produce enough glutamine, such as during injury or infection. In this case we have two ways of getting additional glutamine, that is through food and supplements.
- You can add glutamine-rich foods to your diet to naturally replenish glutamine. Glutamine is found in protein-rich foods such as dairy products, fish, meat, and beans. [4] X Research Source In addition, glutamine is also found in vegetables such as spinach, cabbage and parsley. [5] X Research Source However, the glutamine content in these foods cannot be as much as functional foods.
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Ask your doctor about glutamine supplements. If you do not get enough glutamine through food, or if you need to supplement with glutamine because your body is under a lot of pressure, you should consult your doctor about supplements. The dosage and type of functional food that should be used for each person is not the same, depending on your condition. Your doctor will tell you whether to pursue this treatment, and give you instructions on how much glutamine to take.
- Normally, the dosage of functional foods is 5-10g per day, divided into three doses. [6] X Research source Gleeson M. Dosing and effectiveness of glutamine supplementation in human exercise and sport training. J Nutr. 2008 Oct;138(10):2045S-2049S. However, your doctor may recommend up to 14g.
- People with medical conditions that affect their ability to excrete glutamine, such as kidney or liver disease, should always consult their doctor before starting a new supplement.
- Glutamine supplements are used to deal with a variety of problems, but not all of them have been extensively researched. [7] X Research Sources
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Consider functional foods. Although it’s a good idea to consult with your doctor about supplements, they can be easily purchased at the drugstore without a prescription, usually in two forms, L-glutamine and the latter incorporated in a protein supplement. The product will state whether it is a natural or synthetic extract. There are many varieties that seem to be herbal extracts that are suitable for vegetarians, but you should still check the label.
- Glutamine is available in capsule, powder, liquid or tablet form. Powder and liquid forms are more suitable for people who have difficulty swallowing or want to take glutamine to treat stomatitis. [8] X Research Sources
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Take functional foods properly. There are a few rules you need to follow when taking glutamine. You can drink it on an empty stomach or on an empty stomach, but remember not to take it with hot food or drinks, because glutamine is an amino acid, so it will be affected by temperature. Glutamine should only be taken with cold liquid or at room temperature. [9] X Research Source
- Glutamine powder or liquid can be mixed with water or low-acid fruit juices such as apple or carrot juice. If you drink it with acidic juices (like oranges or lemons) or hot water, the quality of glutamate will degrade and affect its effectiveness. [10] X Research Source
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Understand side effects and warnings. Since glutamine is produced naturally by the body, it rarely causes side effects. However, you should avoid consuming too much glutamine as it can upset the stomach. Consult your doctor before taking glutamine if you have liver or kidney disease, or if you are pregnant or breast-feeding. You may have to reduce the dose or stop taking it altogether.
- In general, it is recommended to avoid taking any supplements in high doses, unless prescribed by your doctor for specific conditions.
- Remember that glutamine is completely different from glutamate, glutamic acid, monosodium glutamate and gluten, so people with gluten intolerance need not worry about a negative reaction to glutamine.
- However, some people may react badly to glutamine in rare cases. Symptoms include abdominal pain, vomiting, headache, sweating, and joint pain. If this happens, you should stop taking glutamine immediately and consult your doctor. [11] X Research Source
Use glutamine for specific cases
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Take glutamine to heal wounds. Supplements are often used to support people who are going through periods of stress due to trauma. Cortisp is a hormone produced by the body during injury, burns, and infection, which causes glutamine levels to drop. Some research shows that glutamine supplements can help support the immune system and counteract the negative effects of wounds. [12] X Trusted Source PubMed Central Go to Source[13] X Trusted Source PubMed Central Go to Source
- Glutamine also reduces infections. Glutamine’s inherent muscle-recovery ability is especially important for patients with burns or recent surgery. [14] X Research Source
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Use glutamine to build muscle. This is a popular functional food for bodybuilders. Just like during an injury, your body experiences similar stress during muscle training. Muscle fibers are temporarily broken down and glutamine and other amino acids are the foundation for new muscle growth after training. It is often thought that it re-energizes and strengthens muscles after a period of intense exercise. [15] X Research Source
- Although this is a common method, there are no studies to confirm the use of glutamine in the process of muscle growth. [16] X Trusted Source PubMed Central Go to Source
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Increased low levels of glutamine caused by cancer. Cancer patients are often deficient in glutamine as well as other micro and macro nutrients. It is because of this deficiency that people are studying the mechanism of action of glutamine supplementation in cancer patients. Currently, glutamine is used for malnourished patients undergoing treatment, and patients receiving bone marrow transplants.
- Some studies suggest that glutamine can treat stomatitis, an inflammation of the mucous membranes in the mouth, and aid in the treatment of chemotherapy-related diarrhea. [17] X Research Source
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Deal with other problems. There are a number of other health problems that many researchers believe glutamine can help with. Patients with ulcerative colitis and Crohn’s disease can take glutamine supplements to support their treatment, [18] X Reliable source PubMed Central Go to source[19] X Research source why glutamine plays a role in the protection of the mucous membrane of the gastrointestinal tract. [20] X Trusted Source PubMed Central Go to Source Take one 5g tablet, six times daily for up to 16 weeks. This dosage should only be taken for a limited time because it is much higher than the usual dose.
- Although there is some evidence that glutamine helps with diarrhea and inflammation of the mucous membranes near the mouth, studies have not proven its effects on other digestive conditions such as Crohn’s disease. [21] X Research Source[22] X Research Source[23] X Research Source
- Glutamine also helps with weight gain in patients with HIV/AIDS. Several studies have shown that when taken with other supplements, glutamine can help with weight gain and muscle mass gain. This is beneficial because HIV/AIDS patients often experience severe weight loss and muscle wasting. In addition, it also helps the patient absorb nutrients better, which is a factor worth considering. [24] X Research Sources
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This article was co-written by Mark Ziats, MD, PhD. Dr. Ziats is an internist, researcher and entrepreneur in biotechnology. He received his PhD in Genetics from the University of Cambridge in 2014 and completed his MD shortly thereafter, at Baylor College of Medicine in 2015.
There are 13 references cited in this article that you can view at the bottom of the page.
This article has been viewed 3,828 times.
Glutamine is an amino acid involved in the production of protein, which is essential for muscle health, endurance and the body’s ability to recover. Although glutamine is produced by the body and also obtained through dietary sources, when the body is under stress, certain cells such as those of the immune system require higher levels of glutamine to function properly. function properly. [1 ] X Research Source Newshpme P. Why is L-glutamine metabpism important to cells of the immune system in health, postinjury, surgery or infection? J Nutr. 2001 Sep;131(9 Suppl):2515S-22S; discussion 2523S-4S.
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